PET
Positron emission tomography (PET)
is a medical diagnostic, imaging procedure that provides physicians with information
about the body’s chemistry, cell function and location of disease – information
not seen through CT, MRI, X-ray,
blood test or physical examination. Unlike CT or MRI, which look at anatomy
or body structure, PET studies body function or the biology of diseases.
How PET is used
PET scans are used by physicians in the fields of oncology, cardiology, neurology
and psychiatry to show various disease states.
- PET can help your oncologist tell if a tumor is cancerous.
- PET enables the cardiologist to screen for heart disease and evaluate damage
from heart attacks.
- PET images can also be used to detect the early signs of neurological diseases.
Technology of PET
As a nuclear medicine technique, PET involves a combination of biochemistry
and technology. Cells in the body rely on glucose as an energy source, and typically,
cells of the body that require more fuel (such as actively growing cancer) will
metabolize glucose at a faster rate than other cells. A radioactive form of
glucose called fluorodeoxyglucose (FDG) is injected into and distributed throughout
the patient's body. The PET scanner then tracks and records the signals the
FDG emits. A computer then reconstructs the signals into whole-body images that
show areas throughout the body where diseases are present. Areas that are metabolizing
more FDG than others will show up on the resulting images.
Origin of PET
PET technology as we know it today was developed in 1973 at Washington University
St. Louis. Dr. Michael Phelps, with the University of California at Los Angeles,
headed a team that built the first PET scanner. In 1983, Ron Nutt, Ph.D., Terry
Douglass, Ph.D., joined Michael Phelps and developed CTI, Inc., a Knoxville,
Tenn.-based company established to move PET technology into the mainstream of
medical imaging. Most developments in PET have originated with CTI, whose founders
are generally considered to be the inventors and developers of clinical PET.
The accuracy of PET scanning eliminates inappropriate treatments as well as
the need for unnecessary surgeries and biopsies, and thus potentially saving
countless lives and billions of dollars every year. Dr. R. Edward Coleman, M.D.
of Duke University Medical Center states, “PET makes a major impact on the clinical
evaluation of cancer patients at Duke University Medical Center. The accuracy
of PET scans in the diagnosis and staging of lung cancer has resulted in the
routine use of PET scans for these indications. PET has resulted in more cost-effective
management of patients by avoiding unnecessary biopsies and surgeries.”
To receive a PET scan a patient should contact their physician.
For general radiology information please call: 763-236-7150 (Mercy) or 763-236-0500 (Elk Ridge Health).
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Elk Ridge Health
14181 Business Center Dr. NW
Elk River, MN 55330
763-236-0500
Source: Mercy & Unity Hospitals, Diagnostic Imaging
First published: 01/01/2005
Last updated: 05/09/2006
Reviewed by: Beverly Jess, Supervisor, Radiology - MRI and Cathy Bergen, Supervisor, Radiology - CT/Special Procedures
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